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Allele : Champ1<em2Lutzy> chromosome alignment maintaining phosphoprotein 1; endonuclease-mediated mutation 2, Cathy Lutz

Primary Identifier  MGI:6392016 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Champ1
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 genome editing is used to introduce a null frameshift mutation. Specifically, a 3 bp deletion followed by a 1 bp insertion and a 9 bp deletion in exon 2 that is predicted to result in an alanine 129 frameshift that adds 43 new amino acids and results in premature termination.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Champ1 Ala129fs43Ter,
  • Champ1 Ala129fs43Ter
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele