Primary Identifier | MGI:6392016 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Champ1 |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 genome editing is used to introduce a null frameshift mutation. Specifically, a 3 bp deletion followed by a 1 bp insertion and a 9 bp deletion in exon 2 that is predicted to result in an alanine 129 frameshift that adds 43 new amino acids and results in premature termination. |