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Protein Coding Gene : Ythdc1 YTH domain containing 1

Primary Identifier  MGI:2443713 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  231386
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable N6-methyladenosine-containing RNA reader activity and mRNA binding activity. Involved in post-transcriptional regulation of gene expression. Acts upstream of or within several processes, including mRNA alternative polyadenylation; primary follicle stage; and regulation of alternative mRNA splicing, via spliceosome. Located in nucleus. Is expressed in brain; intestine; and liver. Orthologous to human YTHDC1 (YTH N6-methyladenosine RNA binding protein C1).
PHENOTYPE: Mice homozygous for a null allele die between E8.5 and E11.5. Mice homozygous for a cconditional allele activated after embryonic development exhibit infertility with defects in spermatogenesis and oogenesis associated with RNA granules and altered transcription in oocytes. [provided by MGI curators]
  • synonyms:
  • A730098D12Rik,
  • RIKEN cDNA A730098D12 gene,
  • Ythdc1,
  • YTH domain containing 1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For