| First Author | Serrano M | Year | 1997 |
| Journal | Exp Cell Res | Volume | 237 |
| Issue | 1 | Pages | 7-13 |
| PubMed ID | 9417860 | Mgi Jnum | J:44752 |
| Mgi Id | MGI:1101266 | Doi | 10.1006/excr.1997.3824 |
| Citation | Serrano M (1997) The tumor suppressor protein p16INK4a. Exp Cell Res 237(1):7-13 |
| abstractText | The tumor suppressor protein p16INK4a (inhibitor of CDK4) is one of the most direct links between cell-cycle control and cancer. The p16INK4a gene is frequently inactivated in human tumors, and inheritance of mutant alleles results in susceptibility to several types of cancer. p16INK4a is part of a cell-cycle regulatory pathway that converges in the tumor suppressor protein Rb. The mechanisms that regulate p16INK4a are starting to be characterized. |
