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Ontology Term : Inhibition of host TAP by virus UniProtKeyword

description  Viral protein involved in the evasion of host adaptive immune response by inhibiting the TAP complex. Transporter associated with antigen (TAP), composed of two subunits TAP1 and TAP2, is required for the translocation of peptides into the ER, where they are loaded onto MHC class I. Thereafter, the viral peptides are presented to cytotoxic T lymphocytes at the cell surface and trigger immune response. The loading of peptide on MHC by TAP is targeted by several viruses including herpesviruses and retroviruses
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Ontology

Ontology Term --> All ancestors

Ontology Term --> All descendants

Ontology Term --> Direct children

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