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Comment :

Type  MGI:General Description  titer of maternal IgG against Itgb3 in homozygous females increases with the number of times females are immunized with wild-type platelets however, homozygous preimmunized females do not show any detectable anti-Itgb3 IgG after the first and second deliveries after mating with wild-type males; low levels of anti-Itgb3 antibodies are seen in the third and subsequent deliveries