Primary Identifier | MGI:2445998 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Del(2Hoxd13)4Ddu |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Hoxd13 and regions XI and XII were deleted via trans-allelic meiotic recombination (TAMERE). The deletion was accomplished by recombination of a single loxP site in the intergenic region between Evx2 and Hoxd13 that had replaced region XII (Evx2/Hoxd13tm3.1Ddu) and a single loxP on the opposite chromosome in the intergenic region between Hoxd12 and Hoxd13 (Hoxdtm3Ddu). |