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Protein Coding Gene : Fgb fibrinogen beta chain

Primary Identifier  MGI:99501 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  110135
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable protein-folding chaperone binding activity and structural molecule activity. Predicted to contribute to cell adhesion molecule binding activity and signaling receptor binding activity. Predicted to be involved in several processes, including blood coagulation; negative regulation of apoptotic process; and positive regulation of secretion by cell. Predicted to act upstream of or within adaptive immune response; hemostasis; and innate immune response. Located in cell cortex. Is active in synapse. Is expressed in several structures, including genitourinary system; gut; liver; lung; and telencephalon. Human ortholog(s) of this gene implicated in cardiovascular system disease (multiple); congenital afibrinogenemia; and end stage renal disease. Orthologous to human FGB (fibrinogen beta chain).
  • synonyms:
  • MGD-MRK-16277,
  • fibrinogen beta chain,
  • 2510049G14Rik,
  • MGI:1915158,
  • Fgb,
  • RIKEN cDNA 2510049G14 gene

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

21 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For