| Primary Identifier | MGI:2384054 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Pafah1b1 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Part of exon 6 and all of exon 7 were replaced with a PGK-neo cassette in the opposite orientation via homologous recombination. The targeted mutation results in deletion of amino acids 164-214 and introduces multiple stop codons into exon 6. Homozygous mutant embryos were observed between E5.5 and E7.5 via Southern blot analysis. |
