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Allele : Tyr<em4Ove> tyrosinase; endonuclease-mediated mutation 4, Paul Overbeek
Primary Identifier  MGI:5817601 Allele Type  Endonuclease-mediated
Attribute String  Hypomorph Gene  Tyr
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology was used to generate a 243-bp deletion in the promoter of the tyrosinase gene, extending from position -323 through -80 with respect to the translation-initiating ATG codon.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • tyro promo (-50/-500)-1D,
  • tyro promo (-50/-500)-1D,
  • OVE modTP-4,
  • OVE modTP-4
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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