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Protein Coding Gene : Insig2 insulin induced gene 2

Primary Identifier  MGI:1920249 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  72999
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable oxysterol binding activity and protein sequestering activity. Acts upstream of or within several processes, including cholesterol biosynthetic process; ear morphogenesis; and negative regulation of lipid biosynthetic process. Predicted to be located in membrane. Predicted to be part of SREBP-SCAP-Insig complex. Predicted to be active in endoplasmic reticulum membrane. Is expressed in central nervous system; jaw bone; and retina. Orthologous to human INSIG2 (insulin induced gene 2).
  • synonyms:
  • Insig-2,
  • Insig2,
  • C730043J18Rik,
  • MGI:2443230,
  • 2900053I11Rik,
  • RIKEN cDNA C730043J18 gene,
  • insulin induced gene 2,
  • RIKEN cDNA 2900053I11 gene

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For