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Protein Coding Gene : Slf2 SMC5-SMC6 complex localization factor 2
Primary Identifier  MGI:1924968 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  226151
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including positive regulation of cellular component organization; positive regulation of double-strand break repair; and protein localization to site of double-strand break. Predicted to act upstream of or within DNA repair. Predicted to be located in PML body. Predicted to be part of chromatin. Predicted to be active in nucleus and site of double-strand break. Human ortholog(s) of this gene implicated in mosaic variegated aneuploidy syndrome. Orthologous to human SLF2 (SMC5-SMC6 complex localization factor 2).
  • synonyms:
  • family with sequence similarity 178, member A,
  • 6030443O07Rik,
  • Slf2,
  • SMC5-SMC6 complex localization factor 2,
  • expressed sequence AU014917,
  • Fam178a,
  • AU014917,
  • MGI:2147633,
  • RIKEN cDNA 6030443O07 gene
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