First Author | Van Snick J | Year | 1989 |
Journal | J Exp Med | Volume | 169 |
Issue | 1 | Pages | 363-8 |
PubMed ID | 2521242 | Mgi Jnum | J:9515 |
Mgi Id | MGI:57975 | Doi | 10.1084/jem.169.1.363 |
Citation | Van Snick J, et al. (1989) Cloning and characterization of a cDNA for a new mouse T cell growth factor (P40). J Exp Med 169(1):363-8 |
abstractText | Recently, we described a murine helper T cell-derived molecule with T cell growth factor activity that is functionally and structurally distinct from IL-2, IL-4, and other known growth factors. This molecule, designated P40, was identified as a glycoprotein capable of supporting antigen-independent growth of certain helper T cell clones. Here, we report the cloning and expression of a cDNA for this new growth factor. The predicted mature protein is a cationic cysteine-rich polypeptide of 14 kD without significant homology to previously sequenced proteins. |