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Protein Coding Gene : Klf10 Kruppel-like transcription factor 10

Primary Identifier  MGI:1101353 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  21847
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables core promoter sequence-specific DNA binding activity. Involved in cellular response to starvation; circadian rhythm; and negative regulation of DNA-templated transcription. Acts upstream of or within several processes, including bone mineralization; positive regulation of osteoclast differentiation; and somatic stem cell population maintenance. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; humerus; and trunk unsegmented mesenchyme. Orthologous to human KLF10 (KLF transcription factor 10).
PHENOTYPE: Homozygous mutants display increased osteoblast formation and impaired osteoblast function. [provided by MGI curators]
  • synonyms:
  • mGIF,
  • AI115143,
  • TGFB inducible early growth response 1,
  • MGD-MRK-36079,
  • expressed sequence AI115143,
  • Kruppel-like transcription factor 10,
  • MGI:2145945,
  • Tieg1,
  • Egral,
  • Klf10,
  • glial cell line derived neurotrophic factor inducible factor,
  • Gdnfif,
  • MGI:107509,
  • early growth response, alpha-like

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For