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Protein Coding Gene : Lpar2 lysophosphatidic acid receptor 2

Primary Identifier  MGI:1858422 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  53978
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables PDZ domain binding activity. Acts upstream of or within G protein-coupled receptor signaling pathway; positive regulation of MAPK cascade; and positive regulation of Rho protein signal transduction. Is active in glutamatergic synapse and presynaptic active zone membrane. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; hemolymphoid system gland; and sensory organ. Orthologous to human LPAR2 (lysophosphatidic acid receptor 2).
PHENOTYPE: Animals homozyogous for a targeted mutation appear phenotypically normal. [provided by MGI curators]
  • synonyms:
  • lysophosphatidic acid receptor 2,
  • endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 4,
  • Edg4,
  • LPA2,
  • Lpar2

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For