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Allele : Pah<em1(IMPC)Tcp> phenylalanine hydroxylase; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:6156602 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Pah
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false Project Collection  IMPC
molecularNote  This allele from project TCPR829 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of ACTATGCTTGAAGTCCGTGC and TGGGCTGCCCACTAGAATAC targeting the 5' side and TGGGCTGCCCACTAGAATAC and TCACACCTAACATTCTTGCA targeting the 3' side of a critical region. This resulted in a 317-bp deletion Chr10:87567166 to 87567482 (GRCm38).
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele