First Author | Xie L | Year | 2005 |
Journal | J Proteome Res | Volume | 4 |
Issue | 6 | Pages | 2088-98 |
PubMed ID | 16335954 | Mgi Jnum | J:106939 |
Mgi Id | MGI:3619793 | Doi | 10.1021/pr050214l |
Citation | Xie L, et al. (2005) Genomic and proteomic analysis of mammary tumors arising in transgenic mice. J Proteome Res 4(6):2088-98 |
abstractText | Transforming growth factor-beta (TGF-beta) is the prototype of a large family of signaling molecules. TGF-beta signaling profoundly influences tumor development as demonstrated in several engineered mouse models. The present study was designed to identify differences by cDNA microarray and MALDI-TOF MS analyses in mammary carcinomas with and without TGF-beta signaling. The results demonstrate a significant potential for combination of profiling technologies to further understand the molecular mechanisms of breast cancer. |