| Primary Identifier | MGI:3609234 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | App |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| description | ES cell line = G1 (Bayer), established from an unspecified 129 subline. |
| molecularNote | A targeting vector was designed such that the locus contains the Swedish/London-FAD mutation and a "humanized" Abeta domain sequence in exons 16-18 under the control of the endogenouse APP promoter. A pA sequence and neomycin resistance gene was included in the vector. |
