| Primary Identifier | MGI:88255 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 11749 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable several functions, including GTP binding activity; cholesterol binding activity; and phospholipid binding activity. Involved in apoptotic signaling pathway and mitochondrial calcium ion homeostasis. Acts upstream of or within calcium ion transport and regulation of muscle contraction. Located in perinuclear region of cytoplasm. Is expressed in blood vessel endothelium; dorsal aorta; lung; primary palate; and yolk sac blood vessel. Orthologous to human ANXA6 (annexin A6). PHENOTYPE: Mice homozygous for a knock-out allele have normal immunological development but exhibit altered cardiomyocyte mechanics and intracellular calcium signaling. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
