First Author | Zacharko RM | Year | 1990 |
Journal | Brain Res | Volume | 533 |
Issue | 2 | Pages | 353-7 |
PubMed ID | 2289151 | Mgi Jnum | J:27331 |
Mgi Id | MGI:74742 | Doi | 10.1016/0006-8993(90)91363-l |
Citation | Zacharko RM, et al. (1990) Stressor induced variations of intracranial self-stimulation from the mesocortex in several strains of mice. Brain Res 533(2):353-7 |
abstractText | Intracranial self-stimulation (ICSS) from the mesocortex was assessed in BALB/cByJ, C57BL/6J and DBA/2J mice immediately, 24 h and again 168 h following stressor application. Stressor exposure failed to influence ICSS performance in C57BL/6J mice, while self-stimulation performance was reduced among BALB/cByJ mice only in the immediate post-stressor interval. In contrast, DBA/2J mice exhibited reduced rates of responding for brain stimulation at each of the post-stressor intervals. The potential contribution of DA alterations to the strain-dependent variations of ICSS performance induced by uncontrollable footshock are discussed. |