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Protein Coding Gene : Il1rap interleukin 1 receptor accessory protein

Primary Identifier  MGI:104975 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  16180
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables interleukin-1 receptor activity and interleukin-33 receptor activity. Involved in several processes, including interleukin-33-mediated signaling pathway; positive regulation of cytokine production; and regulation of synapse assembly. Acts upstream of or within cytokine-mediated signaling pathway. Is active in glutamatergic synapse. Is expressed in several structures, including aorta-gonad-mesonephros; brain ventricle and choroid plexus; forebrain; renal calyx; and ventral grey horn. Orthologous to human IL1RAP (interleukin 1 receptor accessory protein).
PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and grossly normal but show no biological response to IL-1. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI255955,
  • Il1rap,
  • RIKEN cDNA 6430709H04 gene,
  • expressed sequence AV239853,
  • AI255955,
  • MGD-MRK-31048,
  • MGI:2441718,
  • IL-1R AcP,
  • 6430709H04Rik,
  • AV239853,
  • interleukin 1 receptor accessory protein,
  • MGI:2146602,
  • IL-1RAcP,
  • MGI:2146394

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

15 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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