| Primary Identifier | MGI:2148259 | Allele Type | Gene trapped |
| Attribute String | Null/knockout, Reporter | Gene | Dmd |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Insertion of a gene trap vector resulted in aberrant splicing from exon 63 to the inserted Beta-geo gene. RT-PCR analysis demonstrated that the mRNA was mutated in this allele, although a very low level of wild-type transcript was detected in brain. Full length wild-type protein could not be detected by Western blotting in tissue extracts derived from hemizygous males. |
