Primary Identifier | MGI:3655847 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(GFAP-cre)1Kdmc |
Strain of Origin | C57BL/6 x C3H | Is Recombinase | true |
Is Wild Type | false |
molecularNote | A human GFAP promoter was used to drive expression of Cre recombinase, with an intron and polyadenylation signals from the mouse protamine-1 gene. The promoter-cre fragment was surrounded by four copies of a genomic insulator. Cre recombinase expression is restricted to GFAP-positive astrocytes in brain; neurons and oligodendrocytes do not express the Cre protein. |