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Protein Coding Gene : Kat2b K(lysine) acetyltransferase 2B

Primary Identifier  MGI:1343094 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  18519
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables several functions, including N-acetyltransferase activity; cyclin-dependent protein serine/threonine kinase inhibitor activity; and transcription coactivator activity. Involved in positive regulation of glycolytic process; positive regulation of lipid biosynthetic process; and positive regulation of transcription from RNA polymerase II promoter by glucose. Acts upstream of or within positive regulation of gluconeogenesis and positive regulation of transcription by RNA polymerase II. Located in several cellular components, including actomyosin; kinetochore; and sarcomere. Part of ATAC complex. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system gland; and lung. Orthologous to human KAT2B (lysine acetyltransferase 2B).
PHENOTYPE: Mice homozygous for a null allele exhibit no abrnomal phenotype. [provided by MGI curators]
  • synonyms:
  • AI461839,
  • RIKEN cDNA A930006P13 gene,
  • MGI:2147070,
  • expressed sequence AI461839,
  • MGI:2445128,
  • AW536563,
  • A930006P13Rik,
  • expressed sequence AW536563,
  • p300/CBP-associated factor,
  • Kat2b,
  • Pcaf,
  • MGI:2146869,
  • K(lysine) acetyltransferase 2B

Features --> Cross References

Genome

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0 CDSs

0 Exons

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

26 Pathways

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Expression

Gene --> Expression annotations

Phenotype

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Disease

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Literature

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