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Protein Coding Gene : Padi4 peptidyl arginine deiminase, type IV

Primary Identifier  MGI:1338898 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  18602
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables protein-arginine deiminase activity. Involved in nucleosome assembly and stem cell population maintenance. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and nucleus. Is expressed in blastocyst; early embryo; and oocyte. Orthologous to human PADI4 (peptidyl arginine deiminase 4).
PHENOTYPE: Homozygous mice are viable albeit reduced number than expected were born from heterozygous crosses, and shows decreased antibacterial immune responses. Mice homozygous for a different knock-out allele exhibit decreased weight loss in response to viral infection. [provided by MGI curators]
  • synonyms:
  • Pad4,
  • Padi4,
  • PAD type IV,
  • Pdi4,
  • peptidyl arginine deiminase, type IV

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For