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Protein Domain : Membrane-spanning 4-domains subfamily A member 6A-E

Primary Identifier  IPR030427 Type  Family
Short Name  MS4A6A-E
description  MS4A6A/B/C/D/E are members of the membrane-spanning 4-domains family A (MS4A), which contains at least 16 members in human. MS4A6D has been shown to interact with VSIG4 to form a surface signaling complex, which activates JAK2-STAT3-A20 cascades to inhibit NF-kB activation []. MS4A6A and MS4A6E variants have been associated with Alzheimer's disease [, , ].

0 Child Features

1 Parent Features

7 Protein Domain Regions