| Primary Identifier | MGI:96027 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 15135 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable several functions, including heme binding activity; hemoglobin alpha binding activity; and oxygen binding activity. Predicted to contribute to haptoglobin binding activity and peroxidase activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be part of haptoglobin-hemoglobin complex and hemoglobin complex. Is expressed in several structures, including blood; extraembryonic component; genitourinary system; limb; and nervous system. Human ortholog(s) of this gene implicated in delta beta-thalassemia and sickle cell anemia. Orthologous to several human genes including HBE1 (hemoglobin subunit epsilon 1). PHENOTYPE: Mice with disruptions in this gene are grossly normal and viable through adulthood. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
