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Protein Coding Gene : Thoc1 THO complex 1

Primary Identifier  MGI:1919668 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  225160
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable DNA binding activity and RNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to act upstream of or within several processes, including RNA processing; apoptotic process; and mRNA transport. Predicted to be located in cytoplasm and nuclear speck. Predicted to be part of THO complex part of transcription export complex. Predicted to colocalize with chromosome, telomeric region. Is expressed in early conceptus and embryo. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness. Orthologous to human THOC1 (THO complex subunit 1).
PHENOTYPE: Mutations in this gene result in embryonic lethality around implantation in homozygotes. [provided by MGI curators]
  • synonyms:
  • expressed sequence AW107452,
  • NMP-84,
  • RIKEN cDNA 3110002N20 gene,
  • MGI:2147345,
  • Thoc1,
  • 3110002N20Rik,
  • THO complex 1,
  • MGC:28284,
  • AW107452

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For