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Comment :

Type  MGI:General Description  8 of 15 mice show renal cortex pathology indicative of glomerulonephritis, with multifocal infiltration of leukocytes, eosinophilic proteinaceous materials in many glomeruli and adjacent tubules, thicker glomerular basement membrane in affected glomeruli, increased collagen deposition inside glomeruli or in the tubulointerstitium, numerous larger glomeruli as well as a small number of atrophied glomeruli with enlarged Bowman’s spaces