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Allele : Gt(ROSA)26Sor<tm1Mgn> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Mark A Magnuson

Primary Identifier  MGI:5085305 Allele Type  Targeted
Gene  Gt(ROSA)26Sor Transmission  Cell Line
Strain of Origin  129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
description  This allele was used to generate: Gt(ROSA)26Sortm12.1Mgn, Gt(ROSA)26Sortm2.1(mix1b-mCherry)Mgn, Gt(ROSA)26Sortm2Mgn, Gt(ROSA)26Sortm3.1(RARE-CFP)Mgn, Gt(ROSA)26Sortm3(CFP)Mgn, Gt(ROSA)26Sortm4.1(RARE-YFP)Mgn, Gt(ROSA)26Sortm4Mgn, Gt(ROSA)26Sortm5.1(Smad7-CFP)Mgn, Gt(ROSA)26Sortm6.1(Smad7-CFP)Mgn, Gt(ROSA)26Sortm7.1(mix1b-mCherry)Mgn, Gt(ROSA)26Sortm8.1(Ctnnb1-CFP)Mgn
molecularNote  A ~5-kb segment of the gene including the promoter and first exon has been replaced by a lox71/lox2272-flanked pair of selection cassettes encoding a puromycin N-acetyltransferase/truncated HSV1 thymidine kinase fusion protein and neomycin phosphotransferae, respectively expressed under control of the mouse phosphoglycerate kinase promoter and the synthetic bacterial EM7 promoter (Pgk-puro/tk and EM7-neo).
  • mutations:
  • Insertion
  • synonyms:
  • ROSA26<LCA>,
  • ROSA26<LCA>
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1 Feature

Trail: Allele

Genome

0 Expresses

1 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele