| Type | MGI:General | Description | cell cycle analysis on E12.5 fetal gonads showed a significantly higher % of mutant germ (MVH+) cells in G2/M and a corresponding reduction in the % of germ cells in G1 relative to wild-type controls phosphorylated histone H3 and TUNEL labeling, both indicative of G2/M checkpoint activation, are significantly increased in mutant germ cells |
