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Protein Coding Gene : Glra3 glycine receptor, alpha 3 subunit
Primary Identifier  MGI:95749 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  110304
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable extracellularly glycine-gated chloride channel activity and glycine-gated chloride ion channel activity. Predicted to contribute to chloride channel activity. Involved in presynaptic modulation of chemical synaptic transmission. Is active in glycinergic synapse and presynaptic membrane. Is expressed in central nervous system and eye. Orthologous to human GLRA3 (glycine receptor alpha 3).
PHENOTYPE: Homozygous null mice are fertile and display decreased inflammatory pain sensitization without any gross abnormalities in the brain or spinal cord. [provided by MGI curators]
  • synonyms:
  • Glra3,
  • glycine receptor, alpha 3 subunit,
  • MGD-MRK-10132
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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