Primary Identifier | MGI:7490339 | Allele Type | Targeted |
Attribute String | Not Specified | Gene | Ctnnb1 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | LoxP sites were inserted into intron 1 and downstream of exon 15. Exons 2-15 were subsequently replaced with the cDNA sequence coding for exon 2-15 sequence containing a p.T40D mutation. Aspartic acid (D) is a phosphomimic and confers constitutive phosphorylation state upon the encoded peptide. |