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Allele : Tpm3<tm1Pgun> tropomyosin 3, gamma; targeted mutation 1, Peter Gunning

Primary Identifier  MGI:3040795 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tpm3
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A single loxP site remained in place of the first coding exon (1b) and the donor splice junction following the excision of a floxed neo cassette by transient Cre-mediated recombination. This mutation was designed to eliminate all non-muscle type isoforms of the encoded protein. Western blot showed that protein levels in heterozygote brains were the same as that of wild-type.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele