First Author | Ashworth A | Year | 1989 |
Journal | Genomics | Volume | 4 |
Issue | 3 | Pages | 323-7 |
PubMed ID | 2565878 | Mgi Jnum | J:9758 |
Mgi Id | MGI:58215 | Doi | 10.1016/0888-7543(89)90337-6 |
Citation | Ashworth A, et al. (1989) Chromosomal localization of zinc finger protein genes in man and mouse. Genomics 4(3):323-7 |
abstractText | We have determined the mouse and human chromosomal location of a gene (Zfp-3) that codes for a protein that contains potential DNA zinc-binding fingers. An analysis of the segregation of restriction fragment length polymorphisms in recombinant inbred strains and in an interspecific backcross demonstrated that Zfp-3 is located on mouse chromosome 11. Zfp-3 is very closely linked to the Trp53-1 locus but unlinked to another finger protein gene Zfp-4 located on mouse chromosome 8. In humans ZFP3 has been localized to chromosome 17p12-17pter and thus is part of the conserved linkage group between this chromosome and the distal half of mouse chromosome 11. |