| First Author | Hashimoto H | Year | 1996 |
| Journal | Biochim Biophys Acta | Volume | 1281 |
| Issue | 2 | Pages | 129-33 |
| PubMed ID | 8664310 | Mgi Jnum | J:33487 |
| Mgi Id | MGI:80966 | Doi | 10.1016/0005-2736(96)00056-9 |
| Citation | Hashimoto H, et al. (1996) cDNA cloning of a mouse pituitary adenylate cyclase-activating polypeptide receptor. Biochim Biophys Acta 1281(2):129-33 |
| abstractText | A cDNA clone for mouse pituitary adenylate cyclase-activating polypeptide (PACAP) receptor (PACAP-R) was obtained from the brain using reverse transcription-polymerase chain reaction (RT-PCR). The recombinant PACAP receptor expressed in COS cells bound PACAP with about 1000-times higher affinity than vasoactive intestinal polypeptide (VIP), and PACAP stimulated adenylate cyclase through the cloned PACAP receptor. The mouse PACAP receptor consists of 496 amino acids, contains seven transmembrane segments and has 98.4%, 93.0%, and 92.5% identity with the rat, bovine, and human PACAP-R, respectively. |
