Primary Identifier | IPR032929 | Type | Family |
Short Name | ETV3 |
description | Transcriptional repressor ETS translocation variant 3 (ETV3) is a member of the larger E-twenty six (Ets) family whose members bind DNA directly via a conserved Ets domain []. ETV3, also known as Mets or Pe1, regulates growth arrest during terminal macrophage differentiation [, ]. It also represses interstitial collagenase (MMP1) promoter activity []. The Xenopus ETV3 homologue, ETV3L, is required for primary neurogenesis []. |