Primary Identifier | MGI:3663359 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Blm |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A floxed PGK-neomycin resistance gene was inserted into intron 8 and an additional loxP site was placed in intron 7, 75 bp from the start of exon 8. Transient cre expression removed the PGK-neo sequence from correctly targeted ES cells, leaving loxP sites flanking exon 8. |