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Publication : Organization of the rat PACAP gene.

First Author  White SL Year  2000
Journal  Ann N Y Acad Sci Volume  921
Pages  370-2 PubMed ID  11193856
Mgi Jnum  J:67617 Mgi Id  MGI:1930922
Doi  10.1111/j.1749-6632.2000.tb06996.x Citation  White SL, et al. (2000) Organization of the rat PACAP gene. Ann N Y Acad Sci 921:370-2
abstractText  The rat PACAP gene has been isolated, cloned, and sequenced. The gene organization is very similar to that of the mouse and human PACAP genes. An analysis of the 5'-UTR in proPACAP mRNAs indicates that multiple transcripts are generated by using different splice sites within exons 1A, 1B, and 2 to form the 5'-UTR. Analysis of PACAP promoter activity in PC12 cells suggests that forskolin responsiveness of the gene is dependent on elements located between -77 and -413 bp from the transcription start site.
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