First Author | White SL | Year | 2000 |
Journal | Ann N Y Acad Sci | Volume | 921 |
Pages | 370-2 | PubMed ID | 11193856 |
Mgi Jnum | J:67617 | Mgi Id | MGI:1930922 |
Doi | 10.1111/j.1749-6632.2000.tb06996.x | Citation | White SL, et al. (2000) Organization of the rat PACAP gene. Ann N Y Acad Sci 921:370-2 |
abstractText | The rat PACAP gene has been isolated, cloned, and sequenced. The gene organization is very similar to that of the mouse and human PACAP genes. An analysis of the 5'-UTR in proPACAP mRNAs indicates that multiple transcripts are generated by using different splice sites within exons 1A, 1B, and 2 to form the 5'-UTR. Analysis of PACAP promoter activity in PC12 cells suggests that forskolin responsiveness of the gene is dependent on elements located between -77 and -413 bp from the transcription start site. |