| First Author | Okuda K | Year | 1978 |
| Journal | J Exp Med | Volume | 147 |
| Issue | 4 | Pages | 1028-37 |
| PubMed ID | 77304 | Mgi Jnum | J:5981 |
| Mgi Id | MGI:54458 | Doi | 10.1084/jem.147.4.1028 |
| Citation | Okuda K, et al. (1978) A new lymphocyte-activating determinant locus expressed on T cells, and mapping in I-C subregion. J Exp Med 147(4):1028-37 |
| abstractText | A new lymphocyte-activating determinant (Lad) locus expressed on T cells was identified, mapping in the I-C subregions of H-2k and H-2d haplotypes. The mixed lymphocyte reaction stimulation could be inhibited by anti-Ia sera made in strains incompatible for this chromosomal segment. Experiments with purified lymphocyte cell populations suggested that this Lad locus was expressed on T cells. Further, only purified T cells were able to remove the inhibiting activity from the anti-Ia sera. I-C subregion gene(s) seem to code for products selectively expressed on a subpopulation of T cells. |
