Primary Identifier | MGI:2157795 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Il1b |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A PGK-neomycin resistance cassette replaced the first six exons. Northern blot analysis of liver tissue taken three hours after LPS injection did not detect mRNA in sensitized homozygous mutant mice. |