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Protein Domain : ARHGAP6/36, RhoGAP domain

Primary Identifier  IPR041852 Type  Domain
Short Name  ARHGAP6_RhoGAP
description  This entry represent the RhoGAP domain found in ARHGAP6 and ARHGAP36.Rho GTPase activating protein 6 (ARHGAP6/RHOGAP6) shows GAP activity towards RhoA, but not towards Cdc42 and Rac1 []. ARHGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS); MLS is a severe X-linked developmental disorder []. ARHGAP36 is a potent antagonist of PKAsignalling [].

0 Child Features

1 Parent Features

5 Protein Domain Regions