Primary Identifier | MGI:106008 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 11747 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables phosphatidylserine binding activity. Acts upstream of or within response to organic substance. Located in endothelial microparticle and external side of plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and limb. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system; myocardial infarction; and systemic scleroderma. Orthologous to human ANXA5 (annexin A5). PHENOTYPE: Homozygous null mice are viable, fertile, and develop normally. Bone development and maintenance are normal, as are clinical-chemical parameters. [provided by MGI curators] |