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Protein Domain : HAUS complex subunit 5, metazoa

Primary Identifier  IPR026215 Type  Family
Short Name  HAUS5_metazoa
description  Assembly of a robust microtubule-based mitotic spindle is essential for accurate segregation of chromosomes to progeny. Spindle assembly relies on the concerted action of centrosomes, spindle microtubules, molecular motors and non-motor spindle proteins []. A number of novel regulators of spindle assembly have been identified: one of these is HAUS, an 8-subunit protein complex that shares similarity with Drosophila Augmin [, ]. The HAUS (Homologous to AUgmin Subunits) individual subunits have been designated HAUS1 to HAUS8. HAUS5 contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex [, ]. This entry represents HAUS5 from animals.

0 Child Features

1 Parent Features

11 Protein Domain Regions