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Publication : [Studies on the pheromonal pregnancy block in the mouse. II. Discriminatory and/or memorial mechanisms in female mice responding to the stud male].

First Author  Furudate S Year  1981
Journal  Jikken Dobutsu Volume  30
Issue  1 Pages  1-5
PubMed ID  7262197 Mgi Jnum  J:27154
Mgi Id  MGI:74572 Doi  10.1538/expanim1978.30.1_1
Citation  Furudate S, et al. (1981) [Studies on the pheromonal pregnancy block in the mouse. II. Discriminatory and/or memorial mechanisms in female mice responding to the stud male]. Jikken Dobutsu 30(1):1-5
abstractText  The present study was carried out to examine whether the stud male strain have a blocking effect on the pregnancy in stud female. Four inbred mouse strains, C3H, C57BL/6, BALB/c and CBA, were used in these experiments. Virgin female mice were caged together with a male of a different strain at 10-20 weeks of age for copulation. The mated females were removed from the male, and housed with a male strange or alien from the stud male. The Bruce effect was evident in C3H, BALB/c and CBA strains, but not in C57BL/6. It was shown in the strains having the Bruce effect that pregnancy block occurred if the strange male was of a strain different from the stud male. Further experiments were designed to examine whether the Bruce effect might depend on imprinting or memory in a stud female by preproximity to a strange or alien male before stud mating. In this experiment, the Bruce effect did not occur in BALB/c or CBA strain by imprinting from preproximity to the strange or alien male, except for BALB/c males. From these findings, it was suggested that the discrimination or memory must play a leading role in the Bruce effect in that the female was able to recognize her own stud male.
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