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Protein Coding Gene : Cir1 corepressor interacting with RBPJ, 1

Primary Identifier  MGI:1914185 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  66935
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable histone deacetylase binding activity; protein kinase binding activity; and transcription corepressor activity. Acts upstream of or within in utero embryonic development. Predicted to be located in nuclear speck. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Predicted to colocalize with centrosome. Is expressed in genitourinary system; limb bud; and limb ectoderm. Orthologous to human CIR1 (corepressor interacting with RBPJ, CIR1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit a hypocellular placenta, abnormal placental labyrinth vasculature morphology, and complete preweaning lethality. [provided by MGI curators]
  • synonyms:
  • 2810021A19Rik,
  • Cir1,
  • corepressor interacting with RBPJ, 1,
  • RIKEN cDNA 2810021A19 gene,
  • MGI:1922067,
  • 1700023B02Rik,
  • CIR,
  • RIKEN cDNA 1700023B02 gene

Features --> Cross References

Genome

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7 Involved In Mutations

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

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Genes/Features --> Phenotypes (MP terms)

Disease

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