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Allele : Ntan1<tm1Avar> N-terminal Asn amidase; targeted mutation 1, Alexander Varshavsky

Primary Identifier  MGI:2449464 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ntan1
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted by replacement of exons 2-5 with a PGK-neo cassette via homologous recombination. Northern blot analysis detected no expression in brains of homozygous mutant animals, but testes mRNA contained transcripts which apparently lack the 5' half of the open reading frame. Whole mount in-situ hybridization analysis of E9.75 homozygous mutant embryos did not detect any gene expression.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Ntan1<->,
  • Ntan1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories

Trail: Allele