| Type | subunit | Description | Monomer and homodimer; the monomer preferentially binds to CTNNB1 and the homodimer to actin (PubMed:16325583). Component of an cadherin:catenin adhesion complex composed of at least of CDH26, beta-catenin/CTNNB1, alpha-catenin/CTNNA1 and p120 catenin/CTNND1 (By similarity). Possible component of an E-cadherin/ catenin adhesion complex together with E-cadherin/CDH1 and beta-catenin/CTNNB1 or gamma-catenin/JUP; the complex is located to adherens junctions (PubMed:7982500, PubMed:16325582, PubMed:16325583, PubMed:18093941, PubMed:25653389, PubMed:10882138). The stable association of CTNNA1 is controversial as CTNNA1 was shown not to bind to F-actin when assembled in the complex (PubMed:16325582, PubMed:18093941). Alternatively, the CTNNA1-containing complex may be linked to F-actin by other proteins such as LIMA1 (PubMed:18093941). Binds AFDN and F-actin (PubMed:11907041). Interacts with LIMA1 (By similarity) (PubMed:18093941). Interacts with ARHGAP21 (By similarity). Interacts with AJUBA (By similarity). Interacts with vinculin/VCL (By similarity). |
