First Author | Schwabe RF | Year | 2011 |
Journal | Cancer Cell | Volume | 20 |
Issue | 6 | Pages | 698-9 |
PubMed ID | 22172719 | Mgi Jnum | J:178599 |
Mgi Id | MGI:5299352 | Doi | 10.1016/j.ccr.2011.11.021 |
Citation | Schwabe RF, et al. (2011) Targeting Liver Cancer: First Steps toward a miRacle?. Cancer Cell 20(6):698-9 |
abstractText | In a recent issue of Cell, Iliopoulos and colleagues demonstrate a novel and targetable epigenetic amplification loop in hepatocellular carcinoma involving HNF4alpha, miR-124, IL6-R, Stat3, miR-24, and miR-629. These results establish microRNAs as novel players in early stages of hepatocarcinogenesis and as potential targets for the treatment of hepatocellular carcinoma. |