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Publication : Targeting liver cancer: first steps toward a miRacle?

First Author  Schwabe RF Year  2011
Journal  Cancer Cell Volume  20
Issue  6 Pages  698-9
PubMed ID  22172719 Mgi Jnum  J:178599
Mgi Id  MGI:5299352 Doi  10.1016/j.ccr.2011.11.021
Citation  Schwabe RF, et al. (2011) Targeting Liver Cancer: First Steps toward a miRacle?. Cancer Cell 20(6):698-9
abstractText  In a recent issue of Cell, Iliopoulos and colleagues demonstrate a novel and targetable epigenetic amplification loop in hepatocellular carcinoma involving HNF4alpha, miR-124, IL6-R, Stat3, miR-24, and miR-629. These results establish microRNAs as novel players in early stages of hepatocarcinogenesis and as potential targets for the treatment of hepatocellular carcinoma.
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