Primary Identifier | MGI:5050099 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Mcoln1 |
Transmission | Germline | Strain of Origin | 129 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A tetracycline responsive transcriptional activator was place downstream of the promoter followed by a neomycin selection cassette. This insertion replaced exons 1 and 2 and part of exon 3. Northern blot analysis of brain RNA confirmed the absence of mRNA. |