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Protein Coding Gene : Ppm1a protein phosphatase 1A, magnesium dependent, alpha isoform
Primary Identifier  MGI:99878 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  19042
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables phosphoprotein phosphatase activity. Acts upstream of or within cellular response to transforming growth factor beta stimulus; negative regulation of BMP signaling pathway; and positive regulation of protein export from nucleus. Located in cytosol; membrane; and nucleus. Is expressed in several structures, including Peyer's patch; brain; ganglia; male reproductive gland or organ; and white fat. Orthologous to human PPM1A (protein phosphatase, Mg2+/Mn2+ dependent 1A).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit delayed wound healing, delayed re-epithelialization, and decreased keratinocyte migration. [provided by MGI curators]
  • synonyms:
  • AU017636,
  • MPPa-1,
  • RIKEN cDNA 2310003C21 gene,
  • expressed sequence AI427932,
  • MGI:1916736,
  • expressed sequence AU017636,
  • Mpp alpha,
  • RIKEN cDNA 2900017D14 gene,
  • MGI:2144816,
  • MGI:2144943,
  • Ppm1a,
  • 2900017D14Rik,
  • 2310003C21Rik,
  • MGD-MRK-16669,
  • AI427932,
  • MMPa-2,
  • MGI:1920167,
  • protein phosphatase 1A, magnesium dependent, alpha isoform
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